This Phase 1 pilot study at the University of Alabama at Birmingham aimed to determine whether copies of the cystic fibrosis gene (pGT-1) could be delivered to the cells lining the nose of cystic fibrosis patients using cationic liposome (DMRIE/DOPE) mediated gene transfer. Participants were cystic fibrosis patients who were not pregnant, with fertile patients required to use effective contraception. The trial is completed.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
* Cystic fibrosis patients * Not pregnant Fertile patients must use effective contraception