Long-Term Study of Cerebral Glucose Metabolism in Huntington's Disease

Plain-language summary

This study examined the brain's glucose (sugar) metabolism over the long term in Huntington's disease. People with a family history of Huntington's disease who had symptoms or were at risk, along with healthy comparison subjects, could take part. It was carried out as a study with no assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Completed

Sponsor

National Center for Research Resources (NCRR)

Start date

8/1/1993

Related genes

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

PROTOCOL ENTRY CRITERIA:

--Disease Characteristics--

* Documented family history of Huntington's disease (HD)
* Symptomatic HD: chorea required
* At-risk for HD: no detectable systemic or oculomotor abnormality
* Age-matched control subjects
* No history of inherited neurological disease
* No general or neurologic abnormality

--Prior/Concurrent Therapy--

At least 4 weeks since other HD treatment, e.g.:

* Haloperidol
* Benzodiazepine
* Other tranquilizers or neuroleptics

--Patient Characteristics--

* No pregnant women