Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise

Plain-language summary

This study compared weight loss by diet alone with weight loss by diet plus exercise, looking at fatty acid metabolism and insulin sensitivity in premenopausal women with obesity. It was open to women aged 18-45 with a body mass index of 30 or higher. Run by the University of Michigan, it was a study without an assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

University of Michigan

Intervention

Weight loss - diet only, Weight loss plus exercise

Start date

6/1/2003

Estimated completion

1/1/2007

Countries

United States

Related genes

Locations

• Ann Arbor, United States

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Female
* Age = 18-45
* Premenopausal
* Body mass index ≥ 30 kg/m2
* Waist circumference ≥ 100 cm

Exclusion Criteria:

* Evidence of metabolic or cardiovascular disease
* Pregnancy
* Allergies to soybeans or eggs
* Hyperlipidemia (fasting plasma triglyceride concentration \> 125 mg/dl)
* Hematocrit \< 34%