Endothelial Function in Patients With Pulmonary Arterial Hypertension

Plain-language summary

This study examined the function of the inner lining of blood vessels (endothelium) using EndoPAT measurement and blood tests in patients with pulmonary arterial hypertension. It enrolled patients over 18 whose diagnosis was confirmed by right heart catheterization. It was conducted as a trial with no assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

Universitätsklinikum Hamburg-Eppendorf

Intervention

EndoPAT measurement, Blood Test

Start date

10/1/2010

Estimated completion

7/1/2016

Countries

Germany

Related genes

Locations

• Hamburg, Germany

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* proven PH (by right heart catheterization, PAP \>25 mmHg, within last 12 months)
* age \>18 years
* Dana Point classification I or IV (all subgroups)
* declaration of consent

Exclusion Criteria:

* Pulmonary Hypertension not proven by right heart catheterization
* Eisenmenger's syndrome/reaction
* PH other than Dana Point I and IV
* alcohol or drug abuse
* non-compliance due to any cause (e.g. severe psychiatric disorder)