Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis

Plain-language summary

This study examines the role of polymorphisms (genetic variations) in the ATP6V1 gene of the V-ATPase enzyme in the development of incomplete distal renal tubular acidosis. It enrolled people who had one or more episodes of kidney stones (nephrolithiasis) and used a test that measures urinary acidification. It was carried out as a study without an assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Completed

Sponsor

Insel Gruppe AG, University Hospital Bern

Intervention

Furosemide-Fludrocortisone-Test (test for urinary acidification)

Start date

9/1/2012

Estimated completion

5/12/2017

Countries

Switzerland

Related genes

Locations

• Bern, Switzerland

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* One or more episodes of nephrolithiasis

Exclusion Criteria:

* Absence of informed consent
* All conditions affecting renal acidification
* Pregnancy
* Nursing