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This study examines blood biomarkers associated with suicidal behaviour using blood samples collected for genetic purposes. It enrolled people aged 18-65, including those with major depression and a history of suicide attempt as well as comparison groups. It was conducted as a study without a phase and has been completed.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
No specific inclusion criteria : * 18 to 65 years * Subject who signed the informed consent * Able to understand the nature, purpose and methodology of the study * Able to understand and perform the clinical and neuropsychological evaluations. Specific inclusion criteria depressed suicide attempters: * Subject whose primary psychiatric diagnosis is a major depressive episode according to Diagnostic and Statistical Manual of Mental Disorders -5 (DSM-5) criteria * Personal history of suicide attempt affective controls: * Subject whose primary psychiatric diagnosis is a major depressive episode according to DSM-5 criteria * No personal history of suicide attempt healthy controls: * No personal history of psychiatric disorders (Axis I ) defined by the Mini International Neuropsychiatric Interview (MINI) according to the DSM-5 criteria * No history of suicide attempt Exclusion criteria * Refusal of participation * Deprived of liberty Subject (by judicial or administrative decision) * Subject protected by law (guardianship) * Subject exclusion period in relation to another protocol * Subject is not affiliated to a social security scheme, beneficiary or not such a plan * Subject for which the maximum annual amount of allowances of € 4,500 has been reached * Pregnant women * Breastfeeding Women