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This study examines whether diet and exercise can improve blood flow to the brain. It included participants from the Wisconsin Alzheimer's Disease Research Center who did not exercise regularly. It was conducted as a study with no assigned phase and has been completed.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: Participants from the Wisconsin Alzheimer's Disease Research Center (ADRC) - Exclusion Criteria: * . Exclusion criteria are: active lifestyle (exercise \>1 hour/wk); body mass index \> 40; MRI contraindications; history of neurological disease, prior neurosurgery; diagnosed and/or treated type 1 or 2 diabetes; pregnancy; acute or subacute active cardiac disease (ongoing chest pain or myocardial infarction \< 3 months); significant orthopedic or musculoskeletal condition that limits weight bearing.