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Gene Therapy for X-linked Retinitis Pigmentosa (XLRP) - Retinitis Pigmentosa GTPase Regulator (RPGR)

Plain-language summary

This study examines a gene therapy called AAV5-RPGR in males with X-linked retinitis pigmentosa. It was designed for male patients aged 5 and over whose diagnosis was confirmed by a retinal specialist. The study was conducted in Phase 1/Phase 2 and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase
PHASE1/PHASE2
Status
Completed
Sponsor
MeiraGTx UK II Ltd
Intervention
AAV5-RPGR
Start date
7/31/2017
Estimated completion
11/18/2021
Countries
United States, United Kingdom

Related genes

Locations

  • Boston, United States
  • Ann Arbor, United States
  • Pittsburgh, United States
  • Leeds, United Kingdom
  • London, United Kingdom

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Key inclusion Criteria:

* Males aged 5 years or older
* Have X-linked retinitis pigmentosa confirmed by a retinal specialist (CI or PI)

Key exclusion Criteria:

• Have participated in another research study involving an investigational medicinal therapy for ocular disease within the last 6 months
This is not medical advice. Consult your specialist.
View the official record on ClinicalTrials.gov →