Novel Pleural Fluid, Biopsy and Serum Biomarkers for the Investigation of Pleural Effusions

Plain-language summary

This study examines novel pleural fluid, biopsy and blood (serum) biomarkers for investigating pleural effusion, a build-up of fluid between the linings of the lung. Patients with an undiagnosed pleural effusion or pleural thickening requiring investigation, or with suspected lung cancer undergoing bronchoscopy, may take part. It is a study without an assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Completed

Sponsor

University of Oxford

Start date

10/26/2017

Estimated completion

12/31/2019

Countries

United Kingdom

Related genes

Locations

• Oxford, United Kingdom

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Undiagnosed pleural effusion or pleural thickening requiring investigation by one of the following:

  * Pleural aspiration
  * Pleural biopsies from medical thoracoscopy or
  * Ultrasound guided biopsies as part of the clinical plan
* Suspected lung cancer undergoing bronchoscopy and biopsies.

Exclusion Criteria:

* Inability to give written informed consent
* Inability to obtain pleural fluid, blood, endobronchial or pleural biopsies as applicable