Alleviation Of Metabolic Endotoxemia In Adults With Metabolic Syndrome With Milk Fat Globule Membrane

Plain-language summary

This study examines the effect of milk enriched with milk fat globule membrane on metabolic endotoxemia in adults with metabolic syndrome. It included adults who met specific criteria for blood glucose, waist circumference, cholesterol, and blood pressure. It was conducted as a study with no assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

Ohio State University

Intervention

MFGM-enriched full-fat dairy milk, Soy phospholipid/lecithin milk

Start date

7/1/2019

Estimated completion

12/20/2020

Countries

United States

Related genes

Locations

• Columbus, United States

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Serum Glucose 100-126 mg/dl
* Waist C \>89/102 cm; F/M
* Serum HDL-C: \<50/40 mg/dl; F/M
* Serum triglyceride: \>150 mg/dl
* Blood Pressure \>130/85 mmHg

Exclusion Criteria:

* Unstable body mass (±2 kg over prior 3-mo)
* Vegetarian
* Food allergies or lactose intolerance
* User of dietary supplements or probiotics (within past 1-mo)
* Pregnancy, lactation, changes in birth control (within 6-mo)
* Any gastrointestinal disorders
* Chronic diarrhea
* Smoker
* Excess alcohol (\>2 drinks/d)
* Excess aerobic exercise (\>5 h/wk)
* Recent antibiotic or anti-inflammatory agent use
* Blood Pressure \>140/90 mmHg