The Role of TBC1D4 in Exercise- and Insulin-induced Glucose Metabolism in Human Skeletal Muscle

Plain-language summary

This study examines the role of a variant in the TBC1D4 gene in exercise- and insulin-induced sugar (glucose) metabolism in human skeletal muscle, using acute exercise. It enrolled homozygous carriers of the gene variant along with matched non-carrier controls. The study was a non-phased study and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

University of Copenhagen

Intervention

Acute exercise

Start date

10/17/2017

Estimated completion

9/1/2019

Countries

Denmark

Related genes

Locations

• Copenhagen, Denmark

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Homozygote carriers of a pArg684T gene-variant (cases) and matched non carriers (controls)
* BMI between 20-35 kg/m2

Exclusion Criteria:

* Medical treated type 2 diabetes patients