EAS Familial Hypercholesterolaemia Studies Collaboration

Plain-language summary

This is a collaborative study that gathers data from people with familial hypercholesterolaemia into a global registry. It can enroll individuals with a clinical and/or genetic diagnosis of heterozygous or homozygous familial hypercholesterolaemia, as well as relatives who undergo screening. It is a study without an assigned phase and is still recruiting participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Recruiting

Sponsor

Imperial College London

Start date

3/22/2015

Estimated completion

12/1/2030

Countries

United Kingdom

Related genes

Locations

• London, United Kingdom

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Clinical and/or genetic diagnosis of heterozygous or homozygous familial hypercholesterolaemia (FH)
* Relatives of index cases without a diagnosis of FH where screening (cascade or other) is carried out.
* The data have been de-identified prior to transferring to the EAS FHSC Global Registry.

Exclusion Criteria:

* Secondary causes of dyslipidaemia (e.g. untreated hypothyroidism, cholestasis, nephrotic syndrome).
* Where data collection does not conform to the local or country wide standards for anonymised data.