Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia

Plain-language summary

This study examines the use of a research-based genetic test for familial hypercholesterolemia in patients admitted to a cardiac care unit because of a heart attack (myocardial infarction). It enrolled patients under 60 who had a heart attack and elevated LDL cholesterol levels. It was a study with no assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

University of British Columbia

Intervention

Research-based genetic test for Familial Hypercholesterolemia

Start date

1/1/2022

Estimated completion

8/29/2025

Countries

Canada

Related genes

Locations

• Vancouver, Canada
• Vancouver, Canada

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

1. Age \<60 years

   AND
2. Admitted to an acute cardiac unit with either:

   * A ST elevation myocardial infarction (STEMI), or
   * A non-ST elevation myocardial infarction (NSTEMI)

   AND
3. Maximum lipid level at the time of admission or during the prior 1 year of

   * LDL level ≥4 mmol/L (154 mg/dL) if not on a statin, or
   * LDL-C level ≥2.5 mmol/L (96 mg/dL) if on a statin prior to presentation, or
   * Non-HDL-C ≥4.6 mmol/L (177 mg/dL)