Cushing's Syndrome Before and After Treatment (CORRECT)

Plain-language summary

This observational study follows patients with Cushing's syndrome before and after treatment; no drug intervention is given. Adults over 18 with a newly diagnosed endogenous (body-derived) Cushing's syndrome may take part. It is an observational study without an assigned phase and is currently recruiting participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Recruiting

Sponsor

University of Aarhus

Intervention

no intervention, as this is an observational study

Start date

2/16/2023

Estimated completion

11/1/2032

Countries

Denmark

Related genes

Locations

• Aarhus, Denmark

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* New (≤ 2 months) diagnosis of Cushing's syndrome (CS) of endogenous etiology:

  * ACTH-dependent CS
  * ACTH-independent CS
* Age \>18 years
* Written informed consent

Exclusion Criteria:

* Active cancer
* Iatrogenic or malignant cause of CS such as adrenocortical carcinoma
* Chronic heart failure (New York Heart Association class IV)
* Chronic kidney disease Chronic Kidney Disease stage ≥3 (eGFR \>30 ml/min)
* Liver disease in the form of cirrhosis
* Deemed unable to complete the study safely by investigator