The Danish TURNER Cryopreservation Study

Plain-language summary

This study examines the laparoscopic freezing and storage (cryopreservation) of one ovary in children with Turner syndrome. It enrolls girls aged 2-17 with a 45,X or other Turner karyotype whose parents have given consent. It is a trial without an assigned phase and is currently recruiting participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Recruiting

Sponsor

University of Aarhus

Intervention

laparoscopic cryopreservation of one ovary

Start date

1/1/2023

Estimated completion

1/1/2051

Countries

Denmark

Related genes

Locations

• Aarhus, Denmark

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* 45,X karyotype or other Turner variant karyotypes (45,X/46,XX mosaicism, ring X mosaicism, isochromosome X)
* Age 2-17 years old
* Ability to participate in a physical examination including a cardiac examination.
* Signed consent from both parents.

Exclusion Criteria:

* Severe cardiac disease which inhibits safe surgery and pregnancy.
* Karyotype with Y chromosome material
* Mental retardation