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This study examines the relationship between obesity and insulin resistance and persistent post-COVID-19 symptoms (PASC). It enrolls people aged 18-80 with a body mass index of 25 or higher, assessed through adipose tissue biopsy and blood sugar tests. It is a study without an assigned phase and is currently recruiting participants.
The summary above is a plain-language rendering of the official record. The original English title is shown for reference.
Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.
Inclusion Criteria: * Ages 18 to 80 * BMI ≥ 25 kg/m2 * not currently pregnant Exclusion Criteria: Arm 2 (Adipose Tissue Biopsy) exclusions include * pregnancy * prior liposuction * recent change in weight (\> 2 kg in one month) * bleeding disorders * anticoagulant use Arm 3 (healthy controls only) exclusions include patients with * major organ disease * diabetes * history of liposuction * bariatric surgery * eating disorders * psychiatric disorders * pregnancy or lactation * recent change in weight (over the past 12 weeks), * use of weight loss medication or oral steroids * hematocrit \< 33% * fasting glucose \>= 126 mg/dL * blood pressure \>160/100 mmHg