COLPAC (RaDiCo Cohort) (RaDiCo-COLPAC)

Plain-language summary

This is a cohort (observational) study following people with LPAC syndrome (Low Phospholipid Associated Cholelithiasis). It enrolls children and adults who meet the standard or extended diagnostic criteria, while patients who have had a liver transplant are excluded. It is a study with no assigned phase and is currently active but not recruiting new participants (active, not recruiting).

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Active, not recruiting

Sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Start date

11/6/2017

Estimated completion

6/30/2028

Countries

France

Related genes

Locations

• Aix-en-Provence, France
• Annecy, France
• Bobigny, France
• Bordeaux, France
• Bry-sur-Marne, France
• Caen, France
• Clichy, France
• Corbeil-Essonnes, France
• Créteil, France
• Dijon, France
• Grenoble, France
• Lille, France
• Lyon, France
• Orléans, France
• Paris, France
• Poitiers, France
• Reims, France
• Rouen, France
• Strasbourg, France
• Toulouse, France
• Villejuif, France

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Children or adults meeting the standard\* or extended\*\* diagnostic criteria for LPAC syndrome:

  1. First symptoms before the age of 40 years
  2. Radiological images compatible with the existence of intrahepatic lithiasis
  3. Recurrence of symptoms after cholecystectomy

     (\*) standard criteria: symptomatic biliary lithiasis with at least 2 out of 3 criteria

     (\*\*) extended criteria: symptomatic biliary lithiasis with 1 out of 3 criteria

     Exclusion Criteria:
* Patients who have undergone liver transplantation