Gymnema Sylvestre vs Berberine in Obesity Gene Expression of Adipokines

Plain-language summary

This study compares the effects of Gymnema sylvestre and Berberine supplements on adipokine (fat-tissue hormone) gene expression in people with obesity. It included Mexican patients over 18 with a body mass index above 30 and no diabetes diagnosis. It was run as a study with no assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

National Polytechnic Institute, Mexico

Intervention

Berberine, Gymnema sylvestre

Start date

2/1/2016

Estimated completion

2/1/2017

Related genes

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Mexican patients of both sexes, of the over 18 years of age, with a body mass index (BMI) greater than 30 KG/M2 (obesity grade I, II and III), without a previous diagnosis of diabetes mellitus, but with at least two risk factors for the disease (history of parents or siblings, over 40 years of age, sedentary lifestyle habits, controlled arterial hypertension, fasting blood glucose \< 126 mg/dL or glycated hemoglobin \< 6.5%)

Exclusion Criteria:

* pregnant patients,
* diabetics,
* patients with allergic reaction to any components of the supplements