Training for Men Undergoing Androgen Deprivation Therapy.

Plain-language summary

This study examines the effects of a structured exercise program (ADT-train) in men receiving androgen deprivation therapy (ADT) for prostate cancer. It is enrolling men with localized or locally advanced prostate cancer who are planned to receive radiotherapy together with at least six months of ADT. It is being run as a study with no assigned phase and is currently recruiting participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Recruiting

Sponsor

The Swedish School of Sport and Health Sciences

Intervention

ADT-train

Start date

5/1/2024

Estimated completion

12/20/2028

Countries

Sweden

Related genes

Locations

• Stockholm, Sweden

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

1. signed informed consent
2. histologically confirmed localised or locally advanced prostate cancer
3. planned radiotherapy in combination with ADT for at least six months (unfavorable intermediate risk and high-risk prostate cancer) with curative intent and with no known metastasis.

Exclusion Criteria:

1. very high risk localised prostate cancer planned for radiotherapy and ADT plus abiraterone and cortisone
2. localized prostate cancer planned for radiotherapy without ADT
3. on-going or previously treated with ADT or other hormonal treatments
4. have any contraindications to physical testing/exercise as per the ACSM guidelines
5. unable to comply with study procedures