Autophagy/Apoptosis Balance in Placental Vascular Pathologies

Plain-language summary

This study examines the balance between autophagy and apoptosis (cell death) in placental vascular pathologies using blood and urine tests. It enrolls pregnant women who develop a placental vascular complication such as preeclampsia and/or intrauterine growth restriction and give birth at Nimes University Hospital. It is a non-phase study and is currently recruiting participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Recruiting

Sponsor

Centre Hospitalier Universitaire de Nīmes

Intervention

Blood test, Urine test

Start date

5/2/2025

Estimated completion

5/1/2029

Countries

France

Related genes

Locations

• Nîmes, France

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Pregnant women developing a placental vascular complication (preeclampsia and/or intrauterine growth retardation), hospitalized and delivering at Nimes University Hospital.
* Pregnant woman with free and informed consent.
* Pregnant woman affiliated with and/or benefiting from a health insurance scheme.

Exclusion criteria:

* Multiple pregnancy.
* Presence of hypertension and/or proteinuria prior to pregnancy.
* Participant in an interventional drug study.
* Persons in a period of exclusion determined by another study.
* Persons under court protection, guardianship or curatorship.
* Persons unable to give consent.
* Persons for whom it is impossible to give informed information.