Comparison of Cardiometabolic Markers in Individuals With Hypertriglyceridemia With Low and High Weight Loss Responses to an Energy-restricted Diet

Plain-language summary

This study compares cardiometabolic markers in people with hypertriglyceridemia (high blood triglycerides) based on how much weight they lost on a low-calorie diet. It included adults with mild-to-moderate hypertriglyceridemia and a body mass index above 25. It was conducted as a study without an assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

Shahid Beheshti University of Medical Sciences

Intervention

Low-calorie diet

Start date

6/10/2025

Estimated completion

1/27/2026

Countries

Iran

Related genes

Locations

• Tehran, Iran

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* Mild to moderate hypertriglyceridemia (TG=150-500 mg/dL)
* Body mass index (BMI) greater than 25
* Not using fibrates

Exclusion Criteria:

* Advanced chronic kidney disease patients
* Patients with liver cirrhosis
* Unwillingness to continue cooperating with the study
* Any change in the treatment plan during the study, including changes in the type and dose of medications taken or the start of medications that affect blood lipids