Diagnostic and Therapeutic Targets in Cartilaginous Tumours

Plain-language summary

This study explores possible diagnostic and treatment targets in cartilaginous (chondroid) tumours using methods such as tumour tissue analysis and liquid biopsy. It is open to patients with a histologically confirmed cartilaginous tumour, such as an enchondroma, an atypical cartilaginous tumour, or chondrosarcoma of various grades. It is a study without an assigned phase and is currently recruiting participants.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

N/A

Status

Recruiting

Sponsor

St. Anne's University Hospital Brno, Czech Republic

Intervention

Tumour tissue analysis, Molecular validation, Liquid biopsy analysis

Start date

5/1/2025

Estimated completion

12/31/2028

Countries

Czechia

Related genes

Locations

• Brno, Czechia

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria

* Histologically confirmed cartilaginous (chondroid) tumour
* Diagnosis includes one of the following entities (as available and eligible):
* Enchondroma
* Atypical cartilaginous tumour / Grade 1 chondrosarcoma (ACT/G1)
* Conventional chondrosarcoma (Grade 2-3)
* Dedifferentiated chondrosarcoma
* Other rare chondrosarcoma variants (e.g., mesenchymal, clear-cell), if present in the cohort
* Patients treated and/or followed at the First Department of Orthopaedic Surgery, St. Anne's University Hospital Brno

Exclusion Criteria

* Insufficient, degraded, or otherwise unusable tissue samples