Assessment of the Effect of Probiotic Supplementation on Proinflammatory Mechanisms Induced by Systemic Treatment in Women With Breast Cancer

Plain-language summary

This study assessed the effect of probiotic supplementation compared with placebo on the inflammatory (pro-inflammatory) mechanisms triggered by systemic chemotherapy treatment in women with breast cancer. It could include women receiving chemotherapy for the first time who had not used antibiotics or probiotics in the previous 3 months. It was a study without an assigned phase and has been completed.

The summary above is a plain-language rendering of the official record. The original English title is shown for reference.

Trial details

Phase

Not Applicable

Status

Completed

Sponsor

Poznan University of Medical Sciences

Intervention

Probiotic, Placebo

Start date

10/18/2022

Estimated completion

4/30/2024

Countries

Poland

Related genes

Locations

• Poznan, Poland

Eligibility criteria

Criteria are reproduced from the ClinicalTrials.gov record in the original English. Only the trial team can determine eligibility.

Inclusion Criteria:

* first-time chemotherapy
* written consent to participate in the research
* no antibiotic and probiotic therapy in the last 3 months

Exclusion Criteria:

* serious comorbidities (chronic renal failure, diabetes, autoimmune diseasese, unstable coronary artery disease or other cancers)
* previous history of cancer
* smoking cigarettes or using other stimulants
* another probiotic supplementation
* qualification for another type of treatment - surgery or hormone therapy