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Progressive External Ophthalmoplegia

Prevalence: 1/100000

mitochondrial

Official·OMIM:157640 Official·ORPHA254892

Eye muscle paralysis and myopathy due to POLG or TWINKLE gene mutations.

Associated Genes

POLGDNA Polymerase Gamma Catalytic Subunit

Chromosome 15Autosomal Dominant

TWNKTwinkle mtDNA Helicase

Chromosome 10Autosomal Dominant