The information on this page is for informational purposes only and does not constitute medical advice. Consult your genetic counselor or specialist physician for treatment decisions.

ABCB11

—ATP Binding Cassette Subfamily B Member 11

Chromosome: 2

Location: 2:168915498-169031332

OMIM: 603201

Ensembl: ENSG00000073734

Official·OMIM:603201 Official·ENSG00000073734

Encodes bile salt export pump. Mutations cause PFIC type 2.

Treatment Roadmap — ABCB11

Preclinical

Phase 1

1 trial

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Progressive Familial Intrahepatic Cholestasis Type 2

Autosomal RecessivePrevalence: 1/100000hepatic

Official·OMIM:601847 Official·ORPHA284403

Summary

Clinical Trial

Approved Therapy

Registered Variant