The information on this page is for informational purposes only and does not constitute medical advice. Consult your genetic counselor or specialist physician for treatment decisions.

ABCC8

—ATP Binding Cassette Subfamily C Member 8

Chromosome: 11

Location: 11:17392498-17476894

OMIM: 600509

Ensembl: ENSG00000006071

Official·OMIM:600509 Official·ENSG00000006071

Encodes sulfonylurea receptor. Mutations cause neonatal diabetes and congenital hyperinsulinism.

Treatment Roadmap — ABCC8

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Neonatal Diabetes

Autosomal RecessivePrevalence: 1/100000endocrine

Official·OMIM:606176 Official·ORPHA224

Summary

Clinical Trial

Approved Therapy

Registered Variant