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ABL1

—ABL Proto-Oncogene 1

Chromosome: 9

Location: 9:130713043-130887675

OMIM: 189980

Ensembl: ENSG00000097007

Official·OMIM:189980 Official·ENSG00000097007

Encodes tyrosine kinase. Fusion with BCR creates Philadelphia chromosome.

Treatment Roadmap — ABL1

Preclinical

Phase 1

7 trial

Phase 2

18 trial

Phase 3

3 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Chronic Myeloid Leukemia

somaticPrevalence: 1/100000oncologic

Official·OMIM:608232 Official·ORPHA521

Summary

Clinical Trial

Approved Therapy

Registered Variant