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ALK

—ALK Receptor Tyrosine Kinase

Chromosome: 2

Location: 2:29190995-29921586

OMIM: 105590

Ensembl: ENSG00000171094

Official·OMIM:105590 Official·ENSG00000171094

Encodes receptor tyrosine kinase. Translocations are found in lung cancer.

Treatment Roadmap — ALK

Preclinical

Phase 1

15 trial

Phase 2

36 trial

Phase 3

9 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Lung Cancer (ALK-positive)

somaticPrevalence: ~40Koncologic

Official·OMIM:211980

Summary

124

Clinical Trial

Approved Therapy

Registered Variant