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ALOX12B

—Arachidonate 12-Lipoxygenase 12R Type

Chromosome: 17

Location: 17:8068594-8087716

OMIM: 603741

Ensembl: ENSG00000179477

Official·OMIM:603741 Official·ENSG00000179477

Encodes 12R-lipoxygenase enzyme. Mutations cause congenital ichthyosiform erythroderma.

Treatment Roadmap — ALOX12B

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Congenital Ichthyosiform Erythroderma

Autosomal RecessivePrevalence: 1/200000dermatologic

Official·OMIM:242100 Official·ORPHA79394

Summary

Clinical Trial

Approved Therapy

Registered Variant