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APC

—APC Regulator Of WNT Signaling Pathway

Chromosome: 5

Location: 5:112707452-112846239

OMIM: 611731

Ensembl: ENSG00000134982

Official·OMIM:611731 Official·ENSG00000134982

Regulates the Wnt signaling pathway. Mutations cause familial adenomatous polyposis.

Treatment Roadmap — APC

Preclinical

Phase 1

3 trial

Phase 2

11 trial

Phase 3

9 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Familial Adenomatous Polyposis

Autosomal DominantPrevalence: 1/10000oncologic

Official·OMIM:175100 Official·ORPHA733

Summary

Clinical Trial

Approved Therapy

Registered Variant