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BCR

—BCR Activator Of RhoGEF And GTPase

Chromosome: 22

Location: 22:23179704-23318037

OMIM: 151410

Ensembl: ENSG00000186716

Official·OMIM:151410 Official·ENSG00000186716

Encodes GTPase activating protein. Fusion with ABL1 causes chronic myeloid leukemia.

Treatment Roadmap — BCR

Preclinical

Phase 1

30 trial

Phase 2

52 trial

Phase 3

15 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Chronic Myeloid Leukemia

somaticPrevalence: 1/100000oncologic

Official·OMIM:608232 Official·ORPHA521

Summary

166

Clinical Trial

Approved Therapy

Registered Variant