The information on this page is for informational purposes only and does not constitute medical advice. Consult your genetic counselor or specialist physician for treatment decisions.

BEST1

—Bestrophin 1

Chromosome: 11

Location: 11:61949808-61965515

OMIM: 607854

Ensembl: ENSG00000167995

Official·OMIM:607854 Official·ENSG00000167995

Encodes bestrophin-1 chloride channel protein. Mutations cause Best vitelliform macular dystrophy.

Treatment Roadmap — BEST1

Preclinical

Phase 1

1 trial

Phase 2

5 trial

Phase 3

1 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Best Vitelliform Macular Dystrophy

Autosomal DominantPrevalence: 1/10000ophthalmologic

Official·OMIM:153700 Official·ORPHA1243

Summary

Clinical Trial

Approved Therapy

Registered Variant