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BRCA1

—BRCA1 DNA Repair Associated

Chromosome: 17

Location: 17:43044292-43170245

OMIM: 113705

Ensembl: ENSG00000012048

Official·OMIM:113705 Official·ENSG00000012048

Encodes DNA repair protein. Mutations predispose to breast and ovarian cancer.

Treatment Roadmap — BRCA1

Preclinical

Phase 1

15 trial

Phase 2

49 trial

Phase 3

8 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Hereditary Breast-Ovarian Cancer Syndrome

Autosomal DominantPrevalence: 1/500oncologic

Official·OMIM:604370 Official·ORPHA145

Summary

160

Clinical Trial

Approved Therapy

Registered Variant