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BRCA2

—BRCA2 DNA Repair Associated

Chromosome: 13

Location: 13:32315086-32400268

OMIM: 600185

Ensembl: ENSG00000139618

Official·OMIM:600185 Official·ENSG00000139618

Encodes DNA repair protein. Mutations predispose to breast, ovarian, and pancreatic cancer.

Treatment Roadmap — BRCA2

Preclinical

Phase 1

13 trial

Phase 2

36 trial

Phase 3

7 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Hereditary Breast-Ovarian Cancer Syndrome

Autosomal DominantPrevalence: 1/500oncologic

Official·OMIM:604370 Official·ORPHA145

Summary

122

Clinical Trial

Approved Therapy

Registered Variant