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BTK

—Bruton Tyrosine Kinase

Chromosome: X

Location: X:101349338-101390796

OMIM: 300300

Ensembl: ENSG00000010671

Official·OMIM:300300 Official·ENSG00000010671

Encodes Bruton tyrosine kinase. Mutations cause X-linked agammaglobulinemia.

Treatment Roadmap — BTK

Preclinical

Phase 1

6 trial

Phase 2

9 trial

Phase 3

2 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

X-linked Agammaglobulinemia (Bruton)

X-Linked RecessivePrevalence: 1/200000immunologic

Official·OMIM:300755 Official·ORPHA47

Summary

Clinical Trial

Approved Therapy

Registered Variant