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CD40LG

—CD40 Ligand

Chromosome: X

Location: X:136648139-136660390

OMIM: 300386

Ensembl: ENSG00000102245

Official·OMIM:300386 Official·ENSG00000102245

Encodes CD40 ligand. Mutations cause hyper-IgM syndrome type 1.

Treatment Roadmap — CD40LG

Preclinical

Phase 1

4 trial

Phase 2

2 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Hyper-IgM Syndrome

X-Linked RecessivePrevalence: 1/500000immunologic

Official·OMIM:308230 Official·ORPHA101088

Summary

Clinical Trial

Approved Therapy

Registered Variant