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CDKN2A

—Cyclin Dependent Kinase Inhibitor 2A

Chromosome: 9

Location: 9:21966924-21995301

OMIM: 600160

Ensembl: ENSG00000147889

Official·OMIM:600160 Official·ENSG00000147889

Encodes p16 tumor suppressor. Mutations predispose to familial melanoma and pancreatic cancer.

Treatment Roadmap — CDKN2A

Preclinical

Phase 1

1 trial

Phase 2

8 trial

Phase 3

2 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Familial Melanoma

Autosomal DominantPrevalence: 1/10000oncologic

Official·OMIM:155600 Official·ORPHA618

Summary

Clinical Trial

Approved Therapy

Registered Variant