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CLN3

—CLN3 Lysosomal/Endosomal Transmembrane Protein

Chromosome: 16

Location: 16:28474111-28495575

OMIM: 607042

Ensembl: ENSG00000188603

Official·OMIM:607042 Official·ENSG00000188603

Encodes lysosomal transmembrane protein. Mutations cause CLN3 (juvenile Batten) disease.

Treatment Roadmap — CLN3

Preclinical

Phase 1

3 trial

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Neuronal Ceroid Lipofuscinosis Type 3

Autosomal RecessivePrevalence: 1/200000lysosomal

Official·OMIM:204200 Official·ORPHA228346

Summary

Clinical Trial

Approved Therapy

Registered Variant