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COL4A4

—Collagen Type IV Alpha 4 Chain

Chromosome: 2

Location: 2:227002713-227164559

OMIM: 120131

Ensembl: ENSG00000081052

Official·OMIM:120131 Official·ENSG00000081052

Encodes type IV collagen alpha-4 chain. Mutations cause Alport syndrome.

Treatment Roadmap — COL4A4

Preclinical

Phase 1

Phase 2

1 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Alport Syndrome

Autosomal RecessivePrevalence: 1/5000renal

Official·OMIM:301050 Official·ORPHA63

Summary

Clinical Trial

Approved Therapy

Registered Variant