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COL4A5

—Collagen Type IV Alpha 5 Chain

Chromosome: X

Location: X:108439717-108697766

OMIM: 303630

Ensembl: ENSG00000188153

Official·OMIM:303630 Official·ENSG00000188153

Encodes type IV collagen alpha-5 chain. Mutations cause X-linked Alport syndrome.

Treatment Roadmap — COL4A5

Preclinical

Phase 1

Phase 2

2 trial

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Alport Syndrome

X-Linked DominantPrevalence: 1/5000renal

Official·OMIM:301050 Official·ORPHA63

Summary

Clinical Trial

Approved Therapy

Registered Variant