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DICER1

—Dicer 1 Ribonuclease III

Chromosome: 14

Location: 14:95086228-95158010

OMIM: 606241

Ensembl: ENSG00000100697

Official·OMIM:606241 Official·ENSG00000100697

Encodes endonuclease involved in miRNA processing. Mutations cause pleuropulmonary blastoma.

Treatment Roadmap — DICER1

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Pleuropulmonary Blastoma

Autosomal DominantPrevalence: 1/1000000oncologic

Official·OMIM:601200 Official·ORPHA64741

Summary

Clinical Trial

Approved Therapy

Registered Variant