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ERBB2

—Erb-B2 Receptor Tyrosine Kinase 2

Chromosome: 17

Location: 17:39687914-39730426

OMIM: 164870

Ensembl: ENSG00000141736

Official·OMIM:164870 Official·ENSG00000141736

Encodes HER2 receptor. Amplification has prognostic significance in breast cancer.

Treatment Roadmap — ERBB2

Preclinical

Phase 1

44 trial

Phase 2

106 trial

Phase 3

34 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

HER2-Positive Breast Cancer

somaticPrevalence: ~500Koncologic

Official·OMIM:114480

Summary

296

Clinical Trial

Approved Therapy

Registered Variant