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GLB1

—Galactosidase Beta 1

Chromosome: 3

Location: 3:32961103-33097436

OMIM: 611458

Ensembl: ENSG00000170266

Official·OMIM:611458 Official·ENSG00000170266

Encodes beta-galactosidase enzyme. Mutations cause GM1 gangliosidosis.

Treatment Roadmap — GLB1

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

GM1 Gangliosidosis

Autosomal RecessivePrevalence: 1/200000lysosomal

Official·OMIM:230500 Official·ORPHA354

Summary

Clinical Trial

Approved Therapy

Registered Variant