The information on this page is for informational purposes only and does not constitute medical advice. Consult your genetic counselor or specialist physician for treatment decisions.

HEXB

—Hexosaminidase Subunit Beta

Chromosome: 5

Location: 5:74640023-74722647

OMIM: 606873

Ensembl: ENSG00000049860

Official·OMIM:606873 Official·ENSG00000049860

Encodes hexosaminidase B beta subunit. Mutations cause Sandhoff disease.

Treatment Roadmap — HEXB

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Sandhoff Disease

Autosomal RecessivePrevalence: 1/300000lysosomal

Official·OMIM:268800 Official·ORPHA309155

Summary

Clinical Trial

Approved Therapy

Registered Variant