The information on this page is for informational purposes only and does not constitute medical advice. Consult your genetic counselor or specialist physician for treatment decisions.

HFE

—Homeostatic Iron Regulator

Chromosome: 6

Location: 6:26087226-26098343

OMIM: 613609

Ensembl: ENSG00000010704

Official·OMIM:613609 Official·ENSG00000010704

Encodes iron metabolism regulator. C282Y mutation causes hereditary hemochromatosis.

Treatment Roadmap — HFE

Preclinical

Phase 1

2 trial

Phase 2

14 trial

Phase 3

21 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Hereditary Hemochromatosis

Autosomal RecessivePrevalence: 1/200hepatic

Official·OMIM:235200 Official·ORPHA139498

Summary

Clinical Trial

Approved Therapy

Registered Variant