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ICOS

—Inducible T Cell Costimulator

Chromosome: 2

Location: 2:203936757-203961577

OMIM: 604558

Ensembl: ENSG00000163600

Official·OMIM:604558 Official·ENSG00000163600

Encodes T cell co-stimulator. Mutations cause common variable immunodeficiency.

Treatment Roadmap — ICOS

Preclinical

Phase 1

1 trial

Phase 2

1 trial

Phase 3

1 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Common Variable Immunodeficiency

Autosomal RecessivePrevalence: 1/25000immunologic

Official·OMIM:607594 Official·ORPHA1572

Summary

Clinical Trial

Approved Therapy

Registered Variant