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KIT

—KIT Proto-Oncogene

Chromosome: 4

Location: 4:54657267-54740783

OMIM: 164920

Ensembl: ENSG00000157404

Official·OMIM:164920 Official·ENSG00000157404

Encodes stem cell factor receptor. Mutations found in GIST and mastocytosis.

Treatment Roadmap — KIT

Preclinical

Phase 1

9 trial

Phase 2

35 trial

Phase 3

9 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Gastrointestinal Stromal Tumor

somaticPrevalence: 1/100000oncologic

Official·OMIM:606764 Official·ORPHA44890

Summary

258

Clinical Trial

Approved Therapy

Registered Variant