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KRAS

—KRAS Proto-Oncogene

Chromosome: 12

Location: 12:25205246-25326473

OMIM: 190070

Ensembl: ENSG00000133703

Official·OMIM:190070 Official·ENSG00000133703

Encodes GTPase signaling protein. Mutations are prevalent in pancreatic, colon, and lung cancer.

Treatment Roadmap — KRAS

Preclinical

Phase 1

30 trial

Phase 2

53 trial

Phase 3

34 trial

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Colorectal Cancer (KRAS-mutant)

somaticPrevalence: ~500Koncologic

Official·OMIM:114500

Summary

184

Clinical Trial

Approved Therapy

Registered Variant