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LRRK2

—Leucine Rich Repeat Kinase 2

Chromosome: 12

Location: 12:40196744-40369285

OMIM: 609007

Ensembl: ENSG00000188906

Official·OMIM:609007 Official·ENSG00000188906

Encodes leucine-rich repeat kinase 2. G2019S mutation common in Parkinson disease.

Treatment Roadmap — LRRK2

Preclinical

Phase 1

1 trial

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Parkinson Disease (LRRK2-related)

Autosomal DominantPrevalence: ~1Mneurological

Official·OMIM:607060

Summary

Clinical Trial

Approved Therapy

Registered Variant