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MAN2B1

—Mannosidase Alpha Class 2B Member 1

Chromosome: 19

Location: 19:12643831-12666762

OMIM: 609458

Ensembl: ENSG00000104774

Official·OMIM:609458 Official·ENSG00000104774

Encodes alpha-mannosidase enzyme. Mutations cause alpha-mannosidosis.

Treatment Roadmap — MAN2B1

Preclinical

Phase 1

Phase 2

Phase 3

Approved

Clinical trials have approximately 10% success rate. This roadmap shows the current status, not guaranteed outcomes.

Associated Diseases

Alpha-Mannosidosis

Autosomal RecessivePrevalence: 1/500000lysosomal

Official·OMIM:248500 Official·ORPHA61

Summary

Clinical Trial

Approved Therapy

Registered Variant